PhytoCellTec Malus Domestica & Aging: Science Breakthrough or All Hype?

PhytoCellTec™ Malus Domestica.

You've likely heard the word more and more in skincare circles recently, but what is it and what does it do?

The term refers to a liposomal preparation based on the stem cells of a Swiss apple known as the Uttwiler Spätlauber.

This represents the first plant stem cell-based active ingredient that has been evaluated and experimented on human skin. It has been found to protect our own skin cells and improve their longevity, leading to younger looking skin and less damage from aging.

Where do Apple Stem Cells Come From?

uttwiler spatlauber

They don't come from just any apple; the Uttwiler Spätlauber, which was first grown in Northern Switzerland in the 18th Century, was studied by Swiss researchers in much more recent times for its unmatched storability - often appearing and tasting completely fresh or up to four months after being harvested.

Researchers quickly found that the apple's stem cells had unbelievable longevity compared to those from other apples.

For those who aren't aware, humans have stem cells too, which are used to replenish our dying cells, maintain balance within the skin and repair damage.

Over time, these stem cells become less effective, meaning skin begins to wear more easily leading to wrinkles, damaged, saggy skin, and other signs of aging.

It was quickly found that the Swiss apple stem cells helped to protect the human stem cells, making them both more effective at protecting the skin and more longlasting in themselves.

Ever since the stem cells have been snatched up by major cosmetics brands across the world and their effects have been supported by celebrities such as Michelle Obama.

Since the Uttwiler Spätlauber apple is actually very rare and confined to a small area of Switzerland, a local corporation soon came up with a technology known as PhytoCellTec™ which essentially allows them to grow both the Uttwiler Spätlauber apple and any other plant stem cell on a large scale.

So Does it Actually Work? What do Apple Stem Cells Do?

apple stem cells anti aging

There has been a wide range of studies into the effects of apple stem cells and apple stem cell extract on the human skin, with the vast majority of findings being positive.

For example, apple stem cells have been used successfully in laboratory conditions to protect human fibroblasts from aging symptoms and even reverse them

The plant stem cells were also found to increase the viability of umbilical cord blood stem cells and increase the lifespan of human hair follicles.

Stem cells are a huge part of the longevity of the human body, as they are able to both copy themselves and become different forms of cells to replenish the body's supplies.

Embryonic stem cells can grow into any of 220 different cell types from the human body.

Adult stem cells are already used for a range of situations including treatment of leukaemia and severe burns.

The PhytoCellTec™ Malus Domestica fruit cell culture is extracted by first wounding the apple slightly and then harvesting the callus cells that grow over the area. This means the skincare ingredient is high in both metabolites and epigenetic factors which all protect stem cells and assure their longevity, leading to younger and more healthy skin.


the phytocelltec process

PhytoCellTec Malus Domestica Study Results

An in-vitro study into the effects Malus Domestica stem cells would have on human umbilical cord blood stem cells found a positive effect on both the growth and proliferation of the umbilical cord stem cells.

The below graph courtesy of Mibelle Biochemistry shows the stem cell growth experienced in subjects treated with apple stem cells for the skin:

apple stem cell results

Protection Against UV Radiation

We all know that UV radiation is one of the biggest threats to young looking skin and, alongside causing skin cancer, can cause wrinkles, dark spots and speed up aging.

This is why suncream is such a major part of our existing anti-aging routines.

You'll be happy to know, then, that apple stem cells are excellent for blocking and protecting the skin from UV rays. 

A study on different umbilical cord blood cells involved them being incubated with different amounts of apple stem cells and then exposed to UV radiation.

The results found that even with lower amounts of apple stem cells, the umbilical cord blood cells were heavily protected and absorbed drastically less of the UV radiation, experiencing much less damage in the process.

The results seen in this study were even more convincing:

apple stem cells UV radiation

The Age-Delaying Effect on Human Hair Follicles

Human hair follicles are essentially small organs that can be maintained in a growth medium after harvesting to continue growing naturally.

In a study where human follicles were incubated in Malus Domestica, deterioration with age was found to be clearly delayed, and follicles even continued to grow for longer.

Anti-Wrinkle Effects

In another study by Mibelle Biochemistry, the anti-wrinkle effect of green apple stem cells in skincare were evaluated with 20 volunteers.

PhytoCellTec™ Malus Domestica was applied to the crow's feet around the eyes daily for 28 days, with wrinkle depth being measured daily.

100% of these volunteers saw a significant decrease in depth and visibility of wrinkles, with one example of the end result shown below:

Apple Stem Cells Before & After

apple stem cells wrinkles

Benefits of Apple Stem Cells

Based on what we've learnt from the studies above, as well as the numerous others that are out there, there are some benefits of using green apple stem cells that aren't really debatable at this stage, including:

  • Increased longevity and health of skin stem cells
  • Delayed deterioration of skin stem cells caused by age
  • Direct improvement in chronological aging
  • Keeps skin looking youthful and full of vitality
  • Can be easily combined with other ingredients to create innovative skincare formulations

PhytoCellTec is arguably the first major breakthrough in skincare in decades since it is the first scalable active ingredient in the market based on plant stem cells, but unlikely to remain the only one for very long.

How to Use Apple Stem Cells in Skincare

apple stem cell serum

If you've read the above studies in full, and are interested in skincare, the question isn't "should I use apple stem cells?" or even "do apple stem cells work?" but "how should I use them".

After all, the benefits around aging are solid and the results are undeniable, but this doesn't mean other skincare ingredients become obsolete or no longer work.

As a result, it can be a great idea to combine apple stem cells with other active ingredients to make powerful serums that offer anti-aging results that were previously impossible.

For example, our own apple stem cell serum is not just made in the US from high-quality PhytoCell Tec Malus Domestica, but it also contains Witch Hazel, Niacinamide, Pueraria Mirifica extract and other active ingredients.

When looking for apple stem cell cosmetic products to try out and see how they work for you, we recommend looking for similar as this is a sign that a company is trying hard to make a serum or cream that truly works instead of just adding apple stem cells to a product that is otherwise mostly synthetic chemicals and calling it a day, hoping to make a quick buck off the sudden popularity of the ingredient.